We also have to realize that webcomics also mean that there are no barriers to entry anymore. This is a double-edged sword, and both edges are a single molecule thin.
With no barriers, how are people supposed to separate the wheat from the chaff? Hell, how are they even supposed to FIND the wheat IN all the chaff? This is what worries me.
I'm not a tech head, so I'll let others worry about format. What worries me is the market. If those 2500 stores go out of business, what happens to us then? If print comics die, how will we get seen?
When I'm bored and online, I go looking for porn, or something to watch on Hulu. I don't go looking for webcomics. Perhaps I should. Actually, I know I should, since I'll be stepping into that arena shortly. Okay, I know what I'm doing on my next days off...